BBS4, Rabbit, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-130-757	400 μL

Catalog No. 89-130-757 Supplier Abnova Corporation Supplier No. PAB2963

Description

Rabbit polyclonal antibody raised against synthetic peptide of BBS4.

This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse. The similar phenotypes exhibited by mutations in BBS gene family members are likely due to the protein's shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene has sequence similarity to O-linked N-acetylglucosamine (O-GlcNAc) transferases in plants and archaebacteria and in human forms a multi-protein BBSome complex with six other BBS proteins. Alternative splice variants have been described but their predicted protein products have not been experimentally verified

Specifications

• Antigen: BBS4
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of BBS4.
• Dilution: Western Blot (1:1000) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.09% sodium azide)
• Gene: BBS4
• Gene Accession No.: NP_149017;Q96RK4
• Gene Symbols: BBS4
• Host Species: Rabbit
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to internal region of human BBS4.
• Purification Method: Ammonium sulfate precipitation
• Quantity: 400 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 585
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only