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BCL2A1 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No. 89116461 Shop All Abnova Corporation Products
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100 μg
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Catalog No. Quantity
89-116-461 100 μg
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Catalog No. 89-116-461 Supplier Abnova Corporation Supplier No. PAB13212
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Description

Rabbit polyclonal antibody raised against synthetic peptide of BCL2A1.

This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Specifications

Antigen BCL2A1
Applications Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of BCL2A1.
Dilution Western Blot (1-2 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.02% sodium azide)
Gene BCL2A1
Gene Accession No. NP_004040
Gene Alias ACC-1/ACC-2/BCL2L5/BFL1/GRS/HBPA1
Gene Symbols BCL2A1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to N-terminus 14 amino acids of human BCL2A1.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 597
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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