BCL2A1 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-126-090	400 μL

Catalog No. 89-126-090 Supplier Abnova Corporation Supplier No. PAB2438

Description

Rabbit polyclonal antibody raised against synthetic peptide of BCL2A1.

This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Specifications

• Antigen: BCL2A1
• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of BCL2A1.
• Dilution: Western Blot (1:1000) Immunohistochemistry (1:50-100) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.09% sodium azide)
• Gene: BCL2A1
• Gene Accession No.: NP_004040;Q16548
• Gene Alias: ACC-1/ACC-2/BCL2L5/BFL1/GRS/HBPA1
• Gene Symbols: BCL2A1
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to N-terminus of human BCL2A1.
• Purification Method: Protein G purification
• Quantity: 400 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 597
• Test Specificity: BH3 Domain Specific
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only