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BCL2L1 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of BCL2L1.

Manufacturer:  Abnova Corporation PAB18270

Catalog No. 89-119-840


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Description

Description

The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator. [provided by RefSeq

Specifications

Specifications

BCL2L1
1 mg/mL
Rabbit polyclonal antibody raised against synthetic peptide of BCL2L1.
In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Q07817
BCL-XL/S|BCL2L|BCLX|Bcl-X|DKFZp781P2092|bcl-xL|bcl-xS
Rabbit
Affinity purification
RUO
Primary
598
Human, Murine, Rat
ELISA, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
Unconjugated
Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) Immunofluorescence (1:500-1:1000) ELISA (1:5000) The optimal working dilution should be determined by the end user.
BCL2L1
Liquid
BCL2L1
A synthetic peptide corresponding to residues surrounding T47 of human BCL2L1.
100 ug
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Polyclonal
This antibody is specific to BCL2L1.
SDS
Documents
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