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BCL2L1 (phospho S62), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No. 89126949 Shop All Abnova Corporation Products
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89-126-949 100 μg
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Catalog No. 89-126-949 Supplier Abnova Corporation Supplier No. PAB25285
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Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of BCL2L1.

The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator. [provided by RefSeq

Sequence: A-D-Sp-P-A

Specifications

Antigen BCL2L1
Applications Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic phosphopeptide of BCL2L1.
Dilution Immunohistochemistry (1:50-1:100) Western Blot (1:500-1:1000) Immunofluorescence (1:100-1:200) The optimal working dilution should be determined by the end user.
Formulation In PBS (without mg2+ and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene BCL2L1
Gene Accession No. Q07817
Gene Alias BCL-XL/S/BCL2L/BCLX/Bcl-X/DKFZp781P2092/bcl-xL/bcl-xS
Gene Symbols BCL2L1
Host Species Rabbit
Immunogen Synthetic phosphopeptide corresponding to residues surrounding S62 of human BCL2L1.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 598
Target Species Human, Mouse, Rat
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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