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BCL2L1 (phospho T115), Rabbit anti-Mouse, Polyclonal Antibody, Abnova™

Catalog No. 89118696 Shop All Abnova Corporation Products
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100 μg
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89-118-696 100 μg
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Catalog No. 89-118-696 Supplier Abnova Corporation Supplier No. PAB16883
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Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of BCL2L1 .

The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator. [provided by RefSeq

Sequence: TSQLHITpPGTAY

Specifications

Antigen BCL2L1
Applications ELISA
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic phosphopeptide of BCL2L1 .
Dilution ELISA (1:10000-1:100000) The optimal working dilution should be determined by the end user.
Formulation Lyophilized from 10mM PBS
Gene BCL2L1
Gene Alias BCL-XL/S/BCL2L/BCLX/Bcl-X/DKFZp781P2092/bcl-xL/bcl-xS
Gene Symbols BCL2L1
Host Species Rabbit
Immunogen Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T115 of BCL2L1 .
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 598
Target Species Mouse
Content And Storage Store at -20°C on dry atmosphere. After reconstitution with deionized water store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form Lyophilized
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