BCL2L10, Rabbit, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of BCL2L10.

Supplier:  Abnova Corporation PAB12902

Catalog No. 89-116-174

Description

The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway. [provided by RefSeq

Specifications

• Antigen: BCL2L10
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of BCL2L10.
• Formulation: In PBS (0.02% sodium azide)
• Gene Accession No.: NP_065129
• Gene Symbols: BCL2L10
• Immunogen: A synthetic peptide corresponding to amino acids near N-terminus of human BCL2L10.
• Regulatory Status: RUO
• Gene ID (Entrez): 10017
• Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: Immunocytochemistry, Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (1-2 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: BCL2L10
• Gene Alias: BCL-B/Boo/Diva/MGC129810/MGC129811
• Host Species: Rabbit
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

For Research Use Only