BCL2L10, Rabbit, Polyclonal Antibody, Abnova
Rabbit polyclonal antibody raised against synthetic peptide of BCL2L10.
Manufacturer: Abnova Corporation PAB12902
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway. [provided by RefSeq
|Western Blot (1-2 ug/mL) The optimal working dilution should be determined by the end user.|
|A synthetic peptide corresponding to amino acids near N-terminus of human BCL2L10.|
|Immunocytochemistry, Western Blot|
|Rabbit polyclonal antibody raised against synthetic peptide of BCL2L10.|
|In PBS (0.02% sodium azide)|
|Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
For Research Use Only