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BCL2L11 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89114914 Shop All Abnova Corporation Products
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89-114-914 100 μL
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Catalog No. 89-114-914 Supplier Abnova Corporation Supplier No. PAB11195

Rabbit polyclonal antibody raised against synthetic peptide of BCL2L11.

The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq

Specifications

Antigen BCL2L11
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Concentration Lot specific
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of BCL2L11.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:25) The optimal working dilution should be determined by the end user.
Formulation In 10mM PBS, pH 7.4 (1% BSA, 0.09% sodium azide)
Gene BCL2L11
Gene Alias BAM/BIM/BIM-alpha6/BIM-beta6/BIM-beta7/BOD/BimEL/BimL
Gene Symbols BCL2L11
Host Species Rabbit
Immunogen A synthetic peptide corresponding to N-terminus of human BCL2L11.
Purification Method Immunoaffinity purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10018
Target Species Human
Content And Storage Store at 4°C.
Form Liquid
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