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BCL6 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89115426 Shop All Abnova Corporation Products
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89-115-426 100 μL
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Catalog No. 89-115-426 Supplier Abnova Corporation Supplier No. PAB11855

Rabbit polyclonal antibody raised against synthetic peptide of BCL6.

The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq

Specifications

Antigen BCL6
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Concentration Lot specific
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of BCL6.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:50) The optimal working dilution should be determined by the end user.
Formulation In 10mM PBS, pH 7.4 (1% BSA, 0.09% sodium azide)
Gene BCL6
Gene Alias BCL5/BCL6A/LAZ3/ZBTB27/ZNF51
Gene Symbols BCL6
Host Species Rabbit
Immunogen A synthetic peptide corresponding to internal region of human BCL6.
Purification Method Immunoaffinity purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 604
Target Species Human
Content And Storage Store at 4°C.
Form Liquid
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For Research Use Only

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