MilliporeSigma™ Rabbit anti-BCL6, Polyclonal,

Rabbit Polyclonal Antibody

Supplier:  MilliporeSigma™ ABC1480

Catalog No. ABC1480MI

Description

Specifically detects BCL6 in Rat samples, and it is validated for Western Blotting

BCL6 Antibody: BCL6 was first identified as a proto-oncogene in diffuse large B cell lymphoma. BCL6, a transcriptional repressor, plays an important role in lymphomagenesis. It binds Stat recognition-like DNA elements and is required for affinity maturation of mature B cells in germinal centers and Th1/Th2 differentiation, a process that critically depends on BCL6-mediated transcriptional repression of p53. BCL6 is a pharmacological target for eradication of leukemia-initiating cells in chronic myeloid leukemia (CML).

Specifications

• Antigen: BCL6
• Classification: Polyclonal
• Gene Accession No.: P41182
• Host Species: Rabbit
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.

• Applications: Western Blot
• Formulation: Purified rabbit polyclonal in buffer containing PBS (pH 7.2) with 0.02% sodium azide.
• Gene Symbols: BCL6; BCL5; LAZ3; ZBTB27; ZNF51
• Immunogen: BCL6 antibody was raised against an 18 amino acid synthetic peptide near the center of human BCL6.
• Quantity: 100 μg
• Research Discipline: Apoptosis, Cancer
• Target Species: Rat

For Research Use Only