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BIRC7 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89121013 Shop All Abnova Corporation Products
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100 μg
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Catalog No. Quantity
89-121-013 100 μg
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Catalog No. 89-121-013 Supplier Abnova Corporation Supplier No. PAB19488

Description

Rabbit polyclonal antibody raised against synthetic peptide of BIRC7.

The protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide. [provided by RefSeq

Specifications

Antigen BIRC7
Applications Immunocytochemistry, Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of BIRC7.
Dilution Western Blot (1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1 ug/mL) Immunocytochemistry (1 ug/mL) The optimal working dilution should be determined by the end user.
Formulation Lyophilized from 0.9mg NaCl, 0.2mg Na2HPO4 (5mg BSA, 0.05mg sodium azide, 0.05mg Thimerosal)
Gene BIRC7
Gene Alias KIAP/LIVIN/ML-IAP/MLIAP/RNF50
Gene Symbols BIRC7
Host Species Rabbit
Immunogen A synthetic peptide corresponding to amino acids at N-terminus of human BIRC7.
Purification Method Immunoaffinity purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 79444
Test Specificity It different from the mouse sequence by one amino acid.
Target Species Human
Content And Storage Store at -20°C on dry atmosphere. After reconstitution with 200μL of deionized water and concentration will be 500μ/mL store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form Lyophilized
Isotype IgG
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