BIRC7 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-116-149	100 μg

Catalog No. 89-116-149 Supplier Abnova Corporation Supplier No. PAB12872

Description

Rabbit polyclonal antibody raised against synthetic peptide of BIRC7.

The protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide. [provided by RefSeq

Specifications

• Antigen: BIRC7
• Applications: Immunohistochemistry (PFA fixed), Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of BIRC7.
• Dilution: Western Blot (2-4 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.02% sodium azide)
• Gene: BIRC7
• Gene Accession No.: NP_071444
• Gene Alias: KIAP/LIVIN/ML-IAP/MLIAP/RNF50
• Gene Symbols: BIRC7
• Host Species: Rabbit
• Immunogen: A mixture of synthetic peptides corresponding to amino acids 264-280 of the short form and 281-298 of the long form of human BIRC7.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 79444
• Test Specificity: This sequence is identical between a and b forms of the Livin proteins.
• Target Species: Human
• Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only