BLM (phospho T99), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic phosphopeptide of human BLM.

Supplier:  Abnova Corporation PAB29273

Catalog No. 89-130-710

Description

The Bloom syndrome gene product is related to the RecQ subset of DExH box-containing DNA helicases and has both DNA-stimulated ATPase and ATP-dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3'-5' helicase activity. The normal protein may act to suppress inappropriate recombination. [provided by RefSeq]

Specifications

• Antigen: BLM
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of human BLM.
• Formulation: In PBS (without mg²⁺ and Ca²⁺), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
• Gene Accession No.: P54132
• Gene Symbols: BLM
• Immunogen: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T99 of human BLM.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Test Specificity: BLM (phospho T99) polyclonal antibody detects endogenous levels of human BLM only when phosphorylated at threonine 99.
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: Immunohistochemistry (PFA fixed), Western Blot
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (1:50∼1:100) Western Blot (1:500∼1:1000) The optimal working dilution should be determined by the end user.
• Gene: BLM
• Gene Alias: BS/MGC126616/MGC131618/MGC131620/RECQ2/RECQL2/RECQL3
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 641
• Target Species: Human, Mouse, Rat
• Form: Liquid

For Research Use Only