BLNK Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-116-731	100 μg

Catalog No. 89-116-731 Supplier Abnova Corporation Supplier No. PAB13541

Description

Rabbit polyclonal antibody raised against partial recombinant BLNK.

This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Specifications

• Antigen: BLNK
• Applications: Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against partial recombinant BLNK.
• Dilution: The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.4 (0.09% sodium azide)
• Gene: BLNK
• Gene Alias: BASH/BLNK-S/LY57/MGC111051/SLP-65/SLP65
• Gene Symbols: BLNK
• Host Species: Rabbit
• Immunogen: Recombinant protein corresponding to amino acids 171-356 of human BLNK.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 29760
• Test Specificity: This antibody reacts with mouse BLNK, a cytosolic adaptor protein identified as two phosphoproteins migrating at 68 and 70 KDa in SDS PAGE (alternatively spliced forms of human SLP65).
• Target Species: Human, Mouse
• Content And Storage: Store at 4°C. Do not freeze.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only