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Description
This gene is a member of the BCL2/adenovirus E1B 19kDa-interacting protein (BNIP) family. It interacts with the E1B 19kDa protein which is responsible for the protection of virally-induced cell death, as well as E1B 19kDa-like sequences of BCL2, also an apoptotic protector. This gene contains a BH3 domain and a transmembrane domain, which have been associated with pro-apoptotic function. The dimeric mitochondrial protein encoded by this gene is known to induce apoptosis, even in the presence of BCL2. [provided by RefSeq
Specifications
Specifications
| Antigen | BNIP3L, BNIP3 |
| Applications | ELISA, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of BNIP3 (BH3 Domain Specific). |
| Dilution | Western Blot (1:1000) Immunohistochemistry (1:50-100) Immunofluorescence (1:50-100) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS (0.09% sodium azide) |
| Gene | BNIP3 |
| Gene Accession No. | NP_004322 (Gene ID : 665);Q12983 (Gene ID : 664) |
| Gene Alias | NIP3 |
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