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BRAF (phospho T599), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic phosphopeptide of human BRAF.

Supplier:  Abnova Corporation PAB29274

Catalog No. 89-130-711


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Description

Description

This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, nonsmall cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. [provided by RefSeq

Specifications

Specifications

BRAF
Polyclonal
Rabbit polyclonal antibody raised against synthetic phosphopeptide of human BRAF.
In PBS (without mg2+ and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
P15056
BRAF
Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T599 of human BRAF.
100 μL
Primary
BRAF (phospho T599) polyclonal antibody detects endogenous levels of human BRAF only when phosphorylated at threonine 599.
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Immunohistochemistry (PFA fixed)
Unconjugated
Immunohistochemistry (1:50∼1:100) The optimal working dilution should be determined by the end user.
BRAF
B-RAF1/BRAF1/FLJ95109/MGC126806/MGC138284/RAFB1
Rabbit
Affinity Chromatography
RUO
673
Human, Mouse, Rat
Liquid
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