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BRAF (phospho T599), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No. 89130711 Shop All Abnova Corporation Products
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89-130-711 100 μL
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Catalog No. 89-130-711 Supplier Abnova Corporation Supplier No. PAB29274
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Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of human BRAF.

This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, nonsmall cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. [provided by RefSeq

Specifications

Antigen BRAF
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic phosphopeptide of human BRAF.
Dilution Immunohistochemistry (1:50∼1:100) The optimal working dilution should be determined by the end user.
Formulation In PBS (without mg2+ and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene BRAF
Gene Accession No. P15056
Gene Alias B-RAF1/BRAF1/FLJ95109/MGC126806/MGC138284/RAFB1
Gene Symbols BRAF
Host Species Rabbit
Immunogen Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T599 of human BRAF.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 673
Test Specificity BRAF (phospho T599) polyclonal antibody detects endogenous levels of human BRAF only when phosphorylated at threonine 599.
Target Species Human, Mouse, Rat
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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