BRAF Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of BRAF.

Supplier:  Abnova Corporation PAB3946

Catalog No. 89-131-216

Description

This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, nonsmall cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. [provided by RefSeq

Specifications

• Antigen: BRAF
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of BRAF.
• Formulation: In PBS (0.09% sodium azide)
• Gene Accession No.: P15056
• Gene Symbols: BRAF
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to residues surrounding T400 of human BRAF.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:10-50) Western Blot (1:1000) The optimal working dilution should be determined by the end user.
• Gene: BRAF
• Gene Alias: B-RAF1/BRAF1/FLJ95109/MGC126806/MGC138284/RAFB1
• Host Species: Rabbit
• Purification Method: Protein A purification
• Regulatory Status: RUO
• Gene ID (Entrez): 673
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only