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Description
The protein encoded by this gene binds to RNA polymerase II subunit 5 (RPB5) and negatively modulates transcription through its binding to RPB5. The encoded protein seems to have inhibitory effects on various types of activated transcription, but it requires the RPB5-binding region. This protein acts as a corepressor. It is suggested that it may require signaling processes for its function or that it negatively modulates genes in the chromatin structure. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
Specifications
Specifications
| Antigen | C19orf2 |
| Applications | Flow Cytometry, Immunohistochemistry (PFA fixed) |
| Classification | Monoclonal |
| Clone | SP215 |
| Conjugate | Unconjugated |
| Description | Rabbit monoclonal antibody raised against synthetic peptide of C19orf2. |
| Dilution | Flow Cytometry (1:100) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100) The optimal working dilution should be determined by the end user. |
| Formulation | In 10mM PBS, pH 7.6 (1% BSA, 0.09% sodium azide) |
| Gene | C19orf2 |
| Gene Alias | FLJ10575/NNX3/RMP/URI |
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