C4A, Rabbit, Clone: A24-T, Abnova™

Catalog No.	Quantity
89-113-759	100 μL

Catalog No. 89-113-759 Supplier Abnova Corporation Supplier No. MAB9758

Description

Rabbit monoclonal antibody raised against synthetic peptide of C4A.

This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. [provided by RefSeq

Specifications

• Antigen: C4A
• Applications: Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
• Classification: Monoclonal
• Clone: A24-T
• Conjugate: Unconjugated
• Description: Rabbit monoclonal antibody raised against synthetic peptide of C4A.
• Dilution: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100-1:200) The optimal working dilution should be determined by the end user.
• Formulation: In 20mM Tris-HCl, pH 8.0 (20mg/mL BSA, 0.05% sodium azide)
• Gene: C4A
• Gene Accession No.: P0C0L4
• Gene Alias: C4/C4A2/C4A3/C4A4/C4A6/C4S/CO4/CPAMD2/MGC164979/RG
• Gene Symbols: C4A
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to internal region of human C4A.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 720
• Target Species: Mouse
• Content And Storage: Store at 4°C.
• Form: Liquid

For Research Use Only