C4B, Rabbit, Clone: SP91, Abnova™

Catalog No.	Quantity
89-109-236	100 μL

Catalog No. 89-109-236 Supplier Abnova Corporation Supplier No. MAB11022

Description

Rabbit monoclonal antibody raised against synthetic peptide of C4B.

This gene encodes the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. In addition, this gene exists as a long form and a short form due to the presence or absence of a 6.4kb endogenous HERV-K retrovirus in intron 9. [provided by RefSeq

Specifications

• Antigen: C4B
• Applications: Immunohistochemistry (Paraffin)
• Classification: Monoclonal
• Clone: SP91
• Conjugate: Unconjugated
• Description: Rabbit monoclonal antibody raised against synthetic peptide of C4B.
• Dilution: Immunohistochemistry (1:100) The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.6 (1% BSA, 0.09% sodium azide)
• Gene: C4B
• Gene Alias: C4A/C4A13/C4A91/C4B1/C4B12/C4B2/C4B3/C4B5/C4F/CH/CO4/CPAMD3/FLJ60561/MGC164979
• Gene Symbols: C4B
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to C-terminus of human C4B.
• Purification Method: Protein A/G purification
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 721
• Target Species: Human
• Content And Storage: Store at 4°C. Do not freeze.
• Form: Liquid
• Isotype: IgG

For Research Use Only