CA9 Rabbit anti-Dog, Human, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of CA9.

Supplier:  Abnova Corporation PAB12466

Catalog No. 89-115-841

Description

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12. [provided by RefSeq

Specifications

• Antigen: CA9
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of CA9.
• Formulation: In Tris-citrate/phosphate buffer, pH 7.0-8.0 (0.09% sodium azide)
• Gene Accession No.: Q16790
• Gene Symbols: CA9
• Immunogen: A synthetic peptide corresponding to C-terminus of human CA9.
• Regulatory Status: RUO
• Gene ID (Entrez): 768
• Target Species: Canine, Human, Rat
• Form: Liquid

• Applications: Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Frozen), Western Blot
• Conjugate: Unconjugated
• Dilution: Immunofluorescence (1:1000) Immunohistochemistry (Frozen sections) (1:1000) Western Blot (1:2000) The optimal working dilution should be determined by the end user.
• Gene: CA9
• Gene Alias: CAIX/MN
• Host Species: Rabbit
• Quantity: 100 μL
• Primary or Secondary: Primary
• Test Specificity: This antibody is specific to human CA IX.
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only