CA9 Rabbit, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of CA9.

Supplier:  Abnova Corporation PAB4680

Catalog No. 89-131-521

Description

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12. [provided by RefSeq

Specifications

• Antigen: CA9
• Classification: Polyclonal
• Description: carbonic anhydrase IX
• Gene: CA9
• Gene Alias: CAIX, MN
• Host Species: Rabbit
• Purification Method: Protein G purification
• Regulatory Status: RUO
• Gene ID (Entrez): 768
• Content And Storage: Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.

• Applications: ELISA, Western Blot
• Conjugate: Unconjugated
• Formulation: In PBS (0.09% sodium azide)
• Gene Accession No.: NP_001207;Q16790
• Gene Symbols: CA9
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to internal region of human CA9.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Purified

For Research Use Only