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CARD11 Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™

Catalog No. 89116840 Shop All Abnova Corporation Products
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89-116-840 100 μL
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Catalog No. 89-116-840 Supplier Abnova Corporation Supplier No. PAB13783

Description

Rabbit polyclonal antibody raised against CARD11.

The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq

Specifications

Antigen CARD11
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against CARD11.
Dilution The optimal working dilution should be determined by the end user.
Formulation In neat serum
Gene CARD11
Gene Alias BIMP3/CARMA1/MGC133069
Gene Symbols CARD11
Host Species Rabbit
Immunogen Amino acids 1-221 human CARMA1.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84433
Test Specificity Recognizes CARMA1. Detects a band of ∼130 KDa by Western blot.
Target Species Human, Mouse
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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