CARD8 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-116-178	100 μg

Catalog No. 89-116-178 Supplier Abnova Corporation Supplier No. PAB12906

Description

Rabbit polyclonal antibody raised against synthetic peptide of CARD8.

The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. [provided by RefSeq

Specifications

• Antigen: CARD8
• Applications: Immunocytochemistry, Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of CARD8.
• Dilution: Western Blot (2 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.02% sodium azide)
• Gene: CARD8
• Gene Accession No.: AAG50014
• Gene Alias: CARDINAL/DACAR/DKFZp779L0366/Dakar/FLJ18119/FLJ18121/KIAA0955/MGC57162/NDPP/NDPP1/TUCAN
• Gene Symbols: CARD8
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to C-terminus of human CARD8.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 22900
• Test Specificity: An approximate 45 KDa can be detected.
• Target Species: Human
• Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only