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CASP10 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89126474 Shop All Abnova Corporation Products
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100 μL
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89-126-474 100 μL
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Catalog No. 89-126-474 Supplier Abnova Corporation Supplier No. PAB24804
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Description

Rabbit polyclonal antibody raised against synthetic peptide of CASP10.

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq

Specifications

Antigen CASP10
Applications Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of CASP10.
Dilution Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:200) Immunofluorescence (1:50-1:200) The optimal working dilution should be determined by the end user.
Formulation In PBS, pH 7.2 (0.05% sodium azide)
Gene CASP10
Gene Alias ALPS2/FLICE2/MCH4
Gene Symbols CASP10
Host Species Rabbit
Immunogen A synthetic peptide corresponding to CASP10.
Purification Method Antigen affinity purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 843
Test Specificity CASP10 polyclonal antibody detects endogenous levels of CASP10 protein.
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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