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CASP14 Rabbit anti-Dog, Gerbils, Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No. 89114073 Shop All Abnova Corporation Products
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89-114-073 50 μL
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Catalog No. 89-114-073 Supplier Abnova Corporation Supplier No. PAB0250
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Description

Rabbit polyclonal antibody raised against full-length recombinant CASP14.

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier. [provided by RefSeq

Specifications

Antigen CASP14
Applications Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against full length recombinant CASP14.
Dilution The optimal working dilution should be determined by the end user.
Formulation In serum (0.05% sodium azide)
Gene CASP14
Gene Alias MGC119078/MGC119079
Gene Symbols CASP14
Host Species Rabbit
Immunogen Recombinant protein corresponding to full length human CASP14.
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23581
Target Species Canine, Gerbil, Human, Mouse, Rat
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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