CASP3 Rabbit anti-Dog, Gerbils, Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against full-length recombinant CASP3.

Supplier:  Abnova Corporation PAB0243

Catalog No. 89-114-066

Description

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq]

Specifications

• Antigen: CASP3
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against full length recombinant CASP3.
• Formulation: In serum (0.05% sodium azide)
• Gene Alias: CPP32/CPP32B/SCA-1
• Host Species: Rabbit
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Canine, Gerbil, Human, Mouse, Rat
• Form: Liquid

• Applications: Immunohistochemistry (PFA fixed), Immunoprecipitation
• Conjugate: Unconjugated
• Dilution: The optimal working dilution should be determined by the end user.
• Gene: CASP3
• Gene Symbols: CASP3
• Immunogen: Recombinant protein corresponding to full length active human CASP3.
• Regulatory Status: RUO
• Gene ID (Entrez): 836
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only