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CASP5 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89134438 Shop All Abnova Corporation Products
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Catalog No. Quantity
89-134-438 100 μg
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Catalog No. 89-134-438 Supplier Abnova Corporation Supplier No. PAB9827

Description

Rabbit polyclonal antibody raised against synthetic peptide of CASP5.

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein; this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq

Specifications

Antigen CASP5
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description caspase 5, apoptosis-related cysteine peptidase
Formulation In PBS (0.02% sodium azide)
Gene CASP5
Gene Alias ICE(rel)III, ICEREL-III, ICH-3, MGC141966
Gene Symbols CASP5
Host Species Rabbit
Immunogen A synthetic peptide corresponding to N-terminus of human CASP5.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 838
Target Species Human
Content And Storage Store at -20°C. Aliquot to avoid repeated freezing and thawing.
Form Liquid
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