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Description
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase 3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms. [provided by RefSeq
Specifications
Specifications
| Antigen | CASP7 |
| Applications | ELISA, Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of CASP7. |
| Dilution | ELISA (1:10000-1:40000) Western Blot (1:200-1:500) The optimal working dilution should be determined by the end user. |
| Formulation | In buffer containing 0.02% sodium azide |
| Gene | CASP7 |
| Gene Alias | CMH-1/ICE-LAP3/MCH3 |
| Gene Symbols | CASP7 |
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