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Description
This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein
Specifications
Specifications
| Antigen | CASP8AP2 |
| Applications | Immunocytochemistry, Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of CASP8AP2. |
| Dilution | Western Blot (0.25-0.5 ug/mL) Immunocytochemistry (10 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS (0.02% sodium azide) |
| Gene | CASP8AP2 |
| Gene Accession No. | Q9UKL3 |
| Gene Alias | CED-4/FLASH/FLJ11208/KIAA1315/RIP25 |
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For Research Use Only
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