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Description
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade. Alternative splicing results in two transcript variants which encode different isoforms. [provided by RefSeq
Specifications
Specifications
| Antigen | CASP9 |
| Applications | Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of CASP9. |
| Dilution | Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user. |
| Formulation | In 1X PBS, pH 7.2 (0.09% sodium azide) |
| Gene | CASP9 |
| Gene Alias | APAF-3/APAF3/CASPASE-9c/ICE-LAP6/MCH6 |
| Gene Symbols | CASP9 |
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