CASR Rabbit anti-Bovine, Chicken, Dog, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of CASR.

Supplier:  Abnova Corporation PAB26097

Catalog No. 89-127-737

Description

The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism. [provided by RefSeq

Specifications

• Antigen: CASR
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of CASR.
• Formulation: In PBS (0.09% sodium azide)
• Gene Accession No.: P41180
• Gene Symbols: CASR
• Immunogen: A synthetic peptide corresponding to 17 amino acids at N-terminus of human CASR.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Test Specificity: BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Content And Storage: Store at 4°C. For long term storage store at -80°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: Immunohistochemistry (PFA fixed)
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4-8 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: CASR
• Gene Alias: CAR/FHH/FIH/GPRC2A/HHC/HHC1/MGC138441/NSHPT/PCAR1
• Host Species: Rabbit
• Purification Method: Immunoaffinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 846
• Target Species: Bovine, Canine, Chicken, Equine, Hamster, Human, Monkey, Mouse, Porcine, Rabbit, Rat
• Form: Liquid

For Research Use Only