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CASR Rabbit anti-Bovine, Chicken, Dog, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Polyclonal Antibody, Abnova™

Catalog No. 89127737 Shop All Abnova Corporation Products
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50 μg
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89-127-737 50 μg
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Catalog No. 89-127-737 Supplier Abnova Corporation Supplier No. PAB26097
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Description

Rabbit polyclonal antibody raised against synthetic peptide of CASR.

The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism. [provided by RefSeq

Specifications

Antigen CASR
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of CASR.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4-8 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene CASR
Gene Accession No. P41180
Gene Alias CAR/FHH/FIH/GPRC2A/HHC/HHC1/MGC138441/NSHPT/PCAR1
Gene Symbols CASR
Host Species Rabbit
Immunogen A synthetic peptide corresponding to 17 amino acids at N-terminus of human CASR.
Purification Method Immunoaffinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 846
Test Specificity BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Target Species Bovine, Canine, Chicken, Equine, Hamster, Human, Monkey, Mouse, Pig, Rabbit, Rat
Content And Storage Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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