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CAV1 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89115447 Shop All Abnova Corporation Products
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89-115-447 100 μL
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Catalog No. 89-115-447 Supplier Abnova Corporation Supplier No. PAB11900

Description

Rabbit polyclonal antibody raised against synthetic peptide of CAV1.

The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene. [provided by RefSeq

Specifications

Antigen CAV1
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Concentration Lot specific
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of CAV1.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:100) The optimal working dilution should be determined by the end user.
Formulation In 10mM PBS, pH 7.4 (1% BSA, 0.09% sodium azide)
Gene CAV1
Gene Alias BSCL3/CAV/CGL3/MSTP085/VIP21
Gene Symbols CAV1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to C-terminus domain of human CAV1.
Purification Method Immunoaffinity purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 857
Target Species Human
Content And Storage Store at 4°C.
Form Liquid
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