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CAV1 Rabbit anti-Bovine, Dog, Guinea pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Sheep, Polyclonal Antibody, Abnova™

Catalog No. 89118167 Shop All Abnova Corporation Products
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89-118-167 50 μg
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Catalog No. 89-118-167 Supplier Abnova Corporation Supplier No. PAB16293
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Description

Rabbit polyclonal antibody raised against synthetic peptide of CAV1.

The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene. [provided by RefSeq

Specifications

Antigen CAV1
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of CAV1.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (3 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene CAV1
Gene Accession No. Q03135
Gene Alias BSCL3/CAV/CGL3/MSTP085/VIP21
Gene Symbols CAV1
Host Species Rabbit
Immunogen A synthetic peptide (conjugated with KLH) corresponding to human CAV1.
Purification Method Immunoaffinity purification
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 857
Test Specificity N-terminal region of human.
Target Species Bovine, Canine, Equine, Guinea Pig, Human, Monkey, Mouse, Pig, Rabbit, Rat, Sheep
Content And Storage Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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