CAV1 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against synthetic peptide of CAV1.
Supplier: Abnova Corporation PAB26688
The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene. [provided by RefSeqSequence: H-L-Yp-T-V
|Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.|
|Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
|Rabbit polyclonal antibody raised against synthetic peptide of CAV1.|
|In PBS (without mg2+ and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)|
|A synthetic peptide corresponding to residues surrounding Y14 of human CAV1.|
|Human, Mouse, Rat|
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