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CBX5 (phospho S92), Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89130665 Shop All Abnova Corporation Products
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89-130-665 100 μL
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Catalog No. 89-130-665 Supplier Abnova Corporation Supplier No. PAB29230
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Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of human CBX5.

This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq

Specifications

Antigen CBX5
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic phosphopeptide of human CBX5.
Dilution Immunohistochemistry (1:50-1:100) The optimal working dilution should be determined by the end user.
Formulation In PBS, pH 7.4 (without mg2+ and Ca2+), (50% glycerol, 0.02% sodium azide)
Gene CBX5
Gene Accession No. P45973
Gene Alias HP1/HP1A
Gene Symbols CBX5
Host Species Rabbit
Immunogen Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S92 of human CBX5.
Purification Method Affinity purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23468
Test Specificity This antibody detects endogenous levels of CBX5 only when phosphorylated at serine 92.
Target Species Human
Content And Storage Store at -20°C.
Avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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