CBX5 (phospho S92), Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic phosphopeptide of human CBX5.

Supplier:  Abnova Corporation PAB29230

Catalog No. 89-130-665

Description

This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq

Specifications

• Antigen: CBX5
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of human CBX5.
• Formulation: In PBS, pH 7.4 (without mg²⁺ and Ca²⁺), (50% glycerol, 0.02% sodium azide)
• Gene Accession No.: P45973
• Gene Symbols: CBX5
• Immunogen: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S92 of human CBX5.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Test Specificity: This antibody detects endogenous levels of CBX5 only when phosphorylated at serine 92.
• Content And Storage: Store at -20°C.
  Avoid repeated freezing and thawing.

• Applications: Immunohistochemistry (PFA fixed)
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (1:50-1:100) The optimal working dilution should be determined by the end user.
• Gene: CBX5
• Gene Alias: HP1/HP1A
• Host Species: Rabbit
• Purification Method: Affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 23468
• Target Species: Human
• Form: Liquid

For Research Use Only