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Description
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. [provided by RefSeq
Specifications
Specifications
| Antigen | CCL2 |
| Applications | ELISA, Immunohistochemistry, Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against full length recombinant mouse Ccl2. |
| Dilution | ELISA (0.5-2 ug/mL), detection limit 2-4 ng/mL using recombinant mouse CCL2 Immunohistochemistry (2-10 ug/mL) Western Blot (0.1-0.2 ug/mL), detection limit 1.5-3 ng/lane using recombinant mouse CCL2 The optimal working dilution should be determin |
| Formulation | Lyophilized from PBS |
| Gene | CCL2 |
| Gene Accession No. | P13500 |
| Gene Alias | AI323594/HC11/JE/MCAF/MCP-1/MCP1/SMC-CF/Scya2/Sigje |
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