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CCND1 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89115695 Shop All Abnova Corporation Products
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89-115-695 100 μL
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Catalog No. 89-115-695 Supplier Abnova Corporation Supplier No. PAB1229

Description

Rabbit polyclonal antibody raised against full-length recombinant CCND1.

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis. [provided by RefSeq

Specifications

Antigen CCND1
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against full length recombinant CCND1.
Dilution Western Blot (1:1800) The optimal working dilution should be determined by the end user.
Formulation In HEPES, 150mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide)
Gene CCND1
Gene Alias BCL1/D11S287E/PRAD1/U21B31
Gene Symbols CCND1
Host Species Rabbit
Immunogen Recombinant His fusion protein corresponding to full length human CCND1.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 595
Target Species Human
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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