CCND1 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against synthetic peptide of CCND1.
Manufacturer: Abnova Corporation PAB18149
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis. [provided by RefSeq
|Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:40000) The optimal working dilution should be determined by the end user.|
|Human, Murine, Rat|
|ELISA, Immunohistochemistry (PFA fixed), Western Blot|
|Rabbit polyclonal antibody raised against synthetic peptide of CCND1.|
|In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)|
|A synthetic peptide corresponding to human CCND1.|
|This antibody is specific to CCND1.|
Safety and Handling
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok
For Research Use Only