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CCND3, Rabbit, Clone: SP207, Abnova™

Catalog No. 89110315 Shop All Abnova Corporation Products
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Catalog No. Quantity
89-110-315 100 μL
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Catalog No. 89-110-315 Supplier Abnova Corporation Supplier No. MAB12174

Description

Rabbit monoclonal antibody raised against synthetic peptide of human CCND3.

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Specifications

Antigen CCND3
Applications Flow Cytometry, Immunohistochemistry (PFA fixed), Western Blot
Classification Monoclonal
Clone SP207
Conjugate Unconjugated
Description Rabbit monoclonal antibody raised against synthetic peptide of human CCND3.
Dilution Flow Cytometry (1:100) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100) Western Blot (Cell lysate) (1:100) The optimal working dilution should be determined by the end user.
Formulation In 10mM PBS, pH 7.6 (1% BSA, 0.09% sodium azide)
Gene CCND3
Gene Symbols CCND3
Host Species Rabbit
Immunogen A synthetic peptide corresponding to human CCND3.
Purification Method Protein A/G purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 896
Target Species Human
Content And Storage Store at 4°C.
Form Liquid
Isotype IgG
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For Research Use Only

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