CCND3, Rabbit, Clone: SP207, Abnova™

Rabbit monoclonal antibody raised against synthetic peptide of human CCND3.

Supplier:  Abnova Corporation MAB12174

Catalog No. 89-110-315

Description

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Specifications

• Antigen: CCND3
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: Flow Cytometry (1:100) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100) Western Blot (Cell lysate) (1:100) The optimal working dilution should be determined by the end user.
• Gene: CCND3
• Host Species: Rabbit
• Purification Method: Protein A/G purification
• Regulatory Status: RUO
• Gene ID (Entrez): 896
• Content And Storage: Store at 4°C.
• Isotype: IgG

• Applications: Flow Cytometry, Immunohistochemistry (PFA fixed), Western Blot
• Clone: SP207
• Description: Rabbit monoclonal antibody raised against synthetic peptide of human CCND3.
• Formulation: In 10mM PBS, pH 7.6 (1% BSA, 0.09% sodium azide)
• Gene Symbols: CCND3
• Immunogen: A synthetic peptide corresponding to human CCND3.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

For Research Use Only