CCNT1 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of CCNT1.

Supplier:  Abnova Corporation PAB27231

Catalog No. 89-128-886

Description

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin tightly associates with CDK9 kinase, and was found to be a major subunit of the transcription elongation factor p-TEFb. The kinase complex containing this cyclin and the elongation factor can interact with, and act as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and was shown to be both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner were also found to be involved in the phosphorylation and regulation of the carboxy-terminal domain (CTD) of the largest RNA polymerase II subunit. [provided by RefSeq

Specifications

• Antigen: CCNT1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Dilution: Western Blot (1 ug/mL) Immunohistochemistry (2.5 ug/mL) Immunofluorescence (20 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: CCNT1
• Gene Alias: CCNT/CYCT1
• Host Species: Rabbit
• Purification Method: Peptide affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 904
• Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG

• Applications: ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Description: Rabbit polyclonal antibody raised against synthetic peptide of CCNT1.
• Formulation: In PBS (0.02% sodium azide)
• Gene Accession No.: NP_001231
• Gene Symbols: CCNT1
• Immunogen: A synthetic peptide corresponding to 18 amino acids at C-terminus of human CCNT1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Form: Liquid

For Research Use Only