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CCR1 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89127721 Shop All Abnova Corporation Products
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50 μg
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89-127-721 50 μg
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Catalog No. 89-127-721 Supplier Abnova Corporation Supplier No. PAB26081
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Description

Rabbit polyclonal antibody raised against synthetic peptide of CCR1.

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq

Specifications

Antigen CCR1
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of CCR1.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene CCR1
Gene Accession No. P32246
Gene Alias CD191/CKR-1/CKR1/CMKBR1/HM145/MIP1aR/SCYAR1
Gene Symbols CCR1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to 20 amino acids at extracellular domain of human CCR1.
Purification Method Immunoaffinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1230
Test Specificity BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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