CCR10 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-127-720	50 μg

Catalog No. 89-127-720 Supplier Abnova Corporation Supplier No. PAB26080

Description

Rabbit polyclonal antibody raised against synthetic peptide of CCR10.

Chemokines are a group of small (approximately 8 to 14kDa), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27; MIM 604833); CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]).[supplied by OMIM

Specifications

• Antigen: CCR10
• Applications: Immunohistochemistry (PFA fixed)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of CCR10.
• Dilution: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (3-4 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.09% sodium azide)
• Gene: CCR10
• Gene Accession No.: P46092
• Gene Alias: GPR2
• Gene Symbols: CCR10
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to 19 amino acids at C-terminus of human CCR10.
• Purification Method: Immunoaffinity chromatography
• Quantity: 50 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2826
• Test Specificity: BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -80°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only