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Description
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq
Specifications
Specifications
| Antigen | CCR6 |
| Applications | Immunohistochemistry (PFA fixed) |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of CCR6. |
| Dilution | Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS (0.09% sodium azide) |
| Gene | CCR6 |
| Gene Accession No. | P51684 |
| Gene Alias | BN-1/CD196/CKR-L3/CKR6/CKRL3/CMKBR6/DCR2/DRY-6/GPR-CY4/GPR29/GPRCY4/STRL22 |
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