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CCR8 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89127779 Shop All Abnova Corporation Products
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89-127-779 50 μg
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Catalog No. 89-127-779 Supplier Abnova Corporation Supplier No. PAB26138
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Description

Rabbit polyclonal antibody raised against synthetic peptide of CCR8.

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. [provided by RefSeq

Specifications

Antigen CCR8
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of CCR8.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (28 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene CCR8
Gene Accession No. P51685
Gene Alias CDw198/CKR-L1/CKRL1/CMKBR8/CMKBRL2/CY6/GPR-CY6/MGC129966/MGC129973/TER1
Gene Symbols CCR8
Host Species Rabbit
Immunogen A synthetic peptide corresponding to 18 amino acids at N-terminus of human CCR8.
Purification Method Immunoaffinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1237
Test Specificity BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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