CCR8 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of CCR8.

Supplier:  Abnova Corporation PAB26139

Catalog No. 89-127-780

Description

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. [provided by RefSeq

Specifications

• Antigen: CCR8
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of CCR8.
• Formulation: In PBS (0.09% sodium azide)
• Gene Accession No.: P51685
• Gene Symbols: CCR8
• Immunogen: A synthetic peptide corresponding to 19 amino acids at C-terminus of human CCR8.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Test Specificity: BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Content And Storage: Store at 4°C. For long term storage store at -80°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: Immunohistochemistry (PFA fixed)
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (22 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: CCR8
• Gene Alias: CDw198/CKR-L1/CKRL1/CMKBR8/CMKBRL2/CY6/GPR-CY6/MGC129966/MGC129973/TER1
• Host Species: Rabbit
• Purification Method: Immunoaffinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1237
• Target Species: Human
• Form: Liquid

For Research Use Only