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CD244, Rabbit, Polyclonal Antibody, Abnova™

Catalog No. 89120913 Shop All Abnova Corporation Products
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100 μg
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89-120-913 100 μg
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Catalog No. 89-120-913 Supplier Abnova Corporation Supplier No. PAB19379
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Description

Rabbit polyclonal antibody raised against synthetic peptide of CD244.

Natural killer (NK) cells express both activating and inhibitory cell surface receptors. Inhibitory signaling receptors all possess cytoplasmic immunoreceptor tyrosine-based inhibitory motifs, or ITIMs, whereas the activating receptors lack ITIMs and associate with DAP12 (TYROBP; MIM 604142), which contains an immunoreceptor tyrosine-based activation motif, or ITAM. Killer cell immunoglobulin (Ig)-like receptors, or KIRs (see KIR2DL1; MIM 604936), and other NK cell receptors interact with major histocompatibility complex (MHC) molecules (see MIM 142800). Members of the CD2 (MIM 186990) family adhere to each other instead. The cell surface glycoprotein 2B4 is related to CD2 and is implicated in the regulation of NK- and T-cell function (Boles et al., 1999 [PubMed 10458320]).[supplied by OMIM

Specifications

Antigen CD244
Applications ELISA, Immunofluorescence, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of CD244.
Dilution Western Blot (1-2 ug/mL) Immunofluorescence (20 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.02% sodium azide)
Gene CD244
Gene Accession No. NP_1160135
Gene Alias 2B4/NAIL/NKR2B4/Nmrk/SLAMF4
Gene Symbols CD244
Host Species Rabbit
Immunogen A synthetic peptide corresponding to 16 amino acids near C-terminus of human CD244.
Purification Method Peptide affinity purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51744
Test Specificity At least three isoforms of CD244 are known to exist. This antibody is predicted to not cross-react with other SLAM protein family members.
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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