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CD3E Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No. 89134085 Shop All Abnova Corporation Products
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89-134-085 100 μg
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Catalog No. 89-134-085 Supplier Abnova Corporation Supplier No. PAB9003
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Rabbit polyclonal antibody raised against synthetic peptide of CD3E.

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq

Sequence: DYEPIRKGQRDLYSGLNQRRI

Specifications

Antigen CD3E
Applications Dot Blot, ELISA, Immunohistochemistry, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of CD3E.
Dilution ELISA (1:2000) Dot Blot (1:2000) Western Blot (1:500-1:1000) Immunohistochemistry (1:200-1:250) The optimal working dilution should be determined by the end user.
Formulation In buffer containing 0.02% sodium azide
Gene CD3E
Gene Alias FLJ18683/T3E/TCRE
Gene Symbols CD3E
Host Species Rabbit
Immunogen A synthetic peptide (conjugated with KLH) corresponding to amino acids 186-206 of human CD3E.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 916
Target Species Human, Mouse, Rat
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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