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CD40, Rabbit, Clone: 4F1, Abnova™

Catalog No. 89104235 Shop All Abnova Corporation Products
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89-104-235 100 μg
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Catalog No. 89-104-235 Supplier Abnova Corporation Supplier No. H00000958K05
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Description

Rabbit monoclonal antibody raised against a partial recombinant CD40.

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq

Sequence: EPPTACREKQYLINSQCCSLCQPGQKLVSDCTEFTETECLPCGESEFLDTWNRETHCHQHKYCDPNLGLRVQQKGTSETDTICTCEEGWHCTSEACESCVLHRSCSPGFGVKQIATGVSDTICEPCPVGFFSNVSSAFEKCHPWTSCETKDLVVQQAGTNKTDVVCGPQDRLR

Specifications

Antigen CD40
Applications ELISA, Western Blot
Classification Monoclonal
Clone 4F1
Conjugate Unconjugated
Description Rabbit monoclonal antibody raised against a partial recombinant CD40.
Formulation In 1X PBS, pH 7.4
Gene CD40
Gene Accession No. BC012419.1
Gene Alias Bp50/CDW40/MGC9013/TNFRSF5/p50
Gene Symbols CD40
Host Species Rabbit
Immunogen Purified CD40 (AAH12419.1, 21 a.a. - 193 a.a.) human recombinant protein with His-Flag-StrepII tag at N-terminus expressed in human cells.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 958
Target Species Human
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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