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CD68 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89126353 Shop All Abnova Corporation Products
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89-126-353 100 μL
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Catalog No. 89-126-353 Supplier Abnova Corporation Supplier No. PAB24639

Description

Rabbit polyclonal antibody raised against synthetic peptide of CD68.

This gene encodes a 110kDa transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq

Specifications

Antigen CD68
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of CD68.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100) The optimal working dilution should be determined by the end user.
Formulation In PBS, pH 7.6 (1% BSA, 0.09% sodium azide)
Gene CD68
Gene Alias DKFZp686M18236/GP110/SCARD1
Gene Symbols CD68
Host Species Rabbit
Immunogen A synthetic peptide corresponding to internal region of human CD68.
Purification Method Immunogen affinity purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 968
Target Species Human
Content And Storage Store at 4°C. Do not freeze.
Form Liquid
Isotype IgG
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